Anti-NFKBIB

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-70167.60 60 µl -

7 - 16 business days*

158.00€
E-AB-70167.120 120 µl -

7 - 16 business days*

257.00€
E-AB-70167.200 200 µl -

7 - 16 business days*

406.00€
 
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit... more
Product information "Anti-NFKBIB"
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene. Protein function: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. [The UniProt Consortium]
Keywords: Anti-IKBB, Anti-IkB-B, Anti-TRIP-9, Anti-NFKBIB, Anti-IkB-beta, Anti-IkappaBbeta, Anti-NF-kappa-BIB, Anti-I-kappa-B-beta, Anti-TR-interacting protein 9, Anti-NF-kappa-B inhibitor beta, Anti-Thyroid receptor-interacting protein 9, NFKBIB Polyclonal Antibod
Supplier: Elabscience
Supplier-Nr: E-AB-70167

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse IKBß

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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