Anti-NF2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA003097.25	25 µl		-		3 - 8 business days*		330.00€
ATA-HPA003097.100	100 µl		-		3 - 8 business days*		463.00€

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Protein function: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a... more

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Product information "Anti-NF2"

Protein function: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 88%

Keywords:	Anti-NF2, Anti-SCH, Anti-Merlin, Anti-Schwannomin, Anti-Schwannomerlin, Anti-Neurofibromin-2, Anti-Moesin-ezrin-radixin-like protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA003097

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ERRAKQKLLE IATKPTYPPM NPIPAPLPPD IPSFNLIGDS LSFDFKDTDM KRLSMEIEKE KVEYMEKSKH LQEQLNELKT EIEALKLKER ETALDILHNE NSDRGGSSKH NTIKKLTLQS AKSRVA (ATA-APrEST73592)