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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ5899 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The NECTIN1 gene encodes an adhesion... more
Product information "Anti-Nectin 1 / PVRL1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The NECTIN1 gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. Protein function: Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between NECTIN1 and NECTIN3 and between NECTIN1 and NECTIN4. Has some neurite outgrowth-promoting activity. [The UniProt Consortium]
Keywords: | Anti-HveC, Anti-HIgR, Anti-HVEC, Anti-CD111, Anti-Nectin-1, Anti-Herpesvirus entry mediator C, Anti-Herpesvirus Ig-like receptor, Anti-Herpes virus entry mediator C, Anti-Nectin cell adhesion molecule 1, Anti-Poliovirus receptor-related protein 1, Nectin |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ5899 |
Properties
Application: | WB, IHC (paraffin), FC, Direct ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant human protein (amino acids V32-E237) |
Format: | Purified |
Database Information
KEGG ID : | K06081 | Matching products |
UniProt ID : | Q15223 | Matching products |
Gene ID | GeneID 5818 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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