Anti-NDP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA003095.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA003095.100	100 µl		-		7 - 10 business days*		491.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor.... more

Close menu

Product information "Anti-NDP"

Protein function: Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt- dependent activation of FZD4, suggesting the existence of a Wnt- independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 95%

Keywords:	Anti-NDP, Anti-EVR2, Anti-Norrin, Anti-Norrie disease protein, Anti-X-linked exudative vitreoretinopathy 2 protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA003095

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TDSSFIMDSD PRRCMRHHYV DSISHPLYKC SSKMVLLARC EGHCSQASRS EPLVSFSTVL KQPFRSSCHC CRPQTSKLKA LRLRCSGGMR LTATYRYILS CHCEECNS (ATA-APrEST74375)