Anti-NCOA2/SRC2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-345A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A300-345A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Transcriptional coactivator for steroid receptors and nuclear receptors.... more

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Product information "Anti-NCOA2/SRC2"

Protein function: Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF- 2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK- ARNTL/BMAL1 heterodimer. [The UniProt Consortium]

Keywords:	Anti-hTIF2, Anti-NCOA2, Anti-NCoA-2, Anti-bHLHe75, Anti-BHLHE75, Anti-Nuclear receptor coactivator 2, Anti-Transcriptional intermediary factor 2, Anti-Class E basic helix-loop-helix protein 75
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-345A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat)
Immunogen:	synthetic peptide. The epitope recognized by A300-345A-T maps to a region between residues 700 and 750 of human Nuclear Receptor Coactivator 2 using the numbering given in entry NP_006531.1 (GeneID 10499).
Format:	Antigen Affinity Purified