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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| AG-20B-0045-C100 | 100 µg | - |
3 - 9 business days* |
429.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which... more
Product information "Anti-NAIP1/2/5 (mouse), clone Naipa-1"
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor (NLR) family are critical components of the inflammasome that link danger-signals to caspase-1 activation. The NLR member IPAF/NLRC4 senses bacterial flagellin and a conserved type III secretion system (TTSS) rod component. A member of the NLR family, NAIP5 directly and specifically interacts with flagellin, triggers a physical NAIP5-NLRC4 association leading to NLRC4 activation. The related NAIP2 functions analogously to NAIP5, serving as a specific inflammasome receptor for TTSS rod proteins such as Salmonella PrgJ and Burkholderia BsaK.
| Keywords: | Neuronal Apoptosis Inhibitory Protein 1, 2, 5, Baculoviral IAP Repeat-containing Protein 1a, 1b, 1e, Birc 1a, 1b, 1e |
| Supplier: | AdipoGen Life Sciences |
| Supplier-Nr: | AG-20B-0045 |
Properties
| Application: | WB |
| Antibody Type: | Monoclonal |
| Clone: | Naipa-1 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | mouse |
| Immunogen: | Recombinant mouse NAIP5 (BIR2 domain/amino acids 159-227) |
| Format: | Purified |
Database Information
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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