Anti-NAIP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG46306.50	50 µg		-	-	10 - 15 business days*		616.00€

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Protein function: Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7... more

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Product information "Anti-NAIP"

Protein function: Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor-neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor- neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy. [The UniProt Consortium]

Keywords:	Anti-NAIP, Anti-BIRC1, Anti-Neuronal apoptosis inhibitory protein, Anti-Neuronal apoptosis inhibitory protein, Anti-Baculoviral IAP repeat-containing protein 1, Anti-Baculoviral IAP repeat-containing protein 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG46306

Properties

Application:	ICC, IF, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	A 13 amino acid synthetic peptide within aa. 1200 - 1250 of human NAIP
MW:	137 kD
Format:	Affinity Purified