Anti-MYT1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-424A-T	10 µl (2 µg)		-		2 - 8 business days*		178.00€
A302-424A	100 µl		-		2 - 8 business days*		630.00€

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Protein function: Acts as a negative regulator of entry into mitosis (G2 to M transition) by... more

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Product information "Anti-MYT1"

Protein function: Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development. [The UniProt Consortium]

Keywords:	Anti-MYT1, Anti-PKMYT1, Anti-Myt1 kinase, EC=2.7.11.1, Anti-Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-424A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque)
Immunogen:	synthetic peptide. The epitope recognized by A302-424A-T maps to a region between residue 449 and 499 of human membrane associated tyrosine/threonine 1 using the numbering given in entry NP_004194.3 (GeneID 9088).
Format:	Antigen Affinity Purified