Anti-MYSM1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59909.100	100 µl		-	-	10 - 15 business days*		707.00€

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Protein function: Metalloprotease that specifically deubiquitinates monoubiquitinated histone... more

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Product information "Anti-MYSM1"

Protein function: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis and lymphocyte differentiation (PubMed:28115216, PubMed:26220525). [The UniProt Consortium]

Keywords:	Anti-MYSM1, Anti-2A-DUB, Anti-KIAA1915, EC=3.4.19.-, Anti-Histone H2A deubiquitinase MYSM1, Anti-Myb-like, SWIRM and MPN domain-containing protein 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59909

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide within aa. 700 to the C-terminus of Human MYSM1 (NP_001078956.1)
MW:	95 kD
Format:	Affinity Purified