Anti-MYBL2

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R31028 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. V-MYB avian myeloblastosis viral oncogene... more
Product information "Anti-MYBL2"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. V-MYB avian myeloblastosis viral oncogene homolog-like 2, also called MYB-related gene B-MYB, is a protein that in humans is encoded by the MYBL2 gene. The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. Barletta et al.(1991) assigned the gene to chromosome Xq13. However, Noben-Trauth et al.(1996) demonstrated that this assignment was an error. Using mouse Mybl2 cDNA clones as probes, they assigned the gene in an interspecific backcross panel to distal mouse chromosome 2. Using human cDNA probes in combination with fluorescence in situ hybridization analysis, they localized MYBL2 to chromosome 20q13.1, a region that is commonly deleted in myeloid disorders and shows high homology of Synteny to mouse chromosome 2. It has been shown to activate the cell division cycle 2, Cyclin D1, and Insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined. Protein function: Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene. [The UniProt Consortium]
Keywords: Anti-BMYB, Anti-MYBL2, Anti-B-Myb, Anti-Myb-like protein 2, Anti-Myb-related protein B, MYBL2 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R31028

Properties

Application: WB, IHC (paraffin)
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: amino acid sequence from the N-terminus of human MYBL2/B-MYB (MSRRTRCEDLDELHYQD)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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