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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES9858.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES9858.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
caution:The TIAF1 protein is coded in the 3'-UTR region of MYO18A.,function:May be involved in... more
Product information "Anti-MY18A"
caution:The TIAF1 protein is coded in the 3'-UTR region of MYO18A.,function:May be involved in the maintenance of the stromal cell architectures required for cell to cell contact.,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Colocalizes with actin.,subcellular location:Lacks the PDZ domain. Diffusely localized in the cytoplasm.,subunit:Homodimer. Interacts with JAK3 and actin., Protein function: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Golgi apparatus . Golgi apparatus, trans-Golgi network . Golgi outpost . Cytoplasm, cytoskeleton, microtubule organizing center . Recruited to the Golgi apparatus by GOLPH3 (PubMed:19837035). Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). ., [Isoform 1]: Endoplasmic reticulum-Golgi intermediate compartment . Cytoplasm, cytoskeleton . Colocalizes with actin. ., [Isoform 2]: Cytoplasm . Lacks the PDZ domain (PubMed:12761286). Diffusely localized in the cytoplasm (PubMed:12761286). ., [Isoform 5]: Cell surface .
Keywords: | Anti-MAJN, Anti-SP-R210, Anti-Unconventional myosin-XVIIIa, Anti-Myosin containing a PDZ domain, Anti-Surfactant protein receptor SP-R210, Anti-Molecule associated with JAK3 N-terminus, MY18A rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES9858 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from human protein . at AA range: 1920-2000 |
MW: | 225 kD |
Format: | Purified |
Database Information
KEGG ID : | K10362 | Matching products |
UniProt ID : | Q92614 | Matching products |
Gene ID | GeneID 399687 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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