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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
M2197-04.100 | 100 µg | - | - |
3 - 19 business days* |
962.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
MUNC18-2 (Syntaxin-binding protein 2, STXBP2, Unc18-2, Unc18B) is a 64-66kD member of the... more
Product information "Anti-MUNC18-2 (Syntaxin-binding protein 2, Syntaxin-BP2, STXBP2, Hunc18b, Unc18-2)"
MUNC18-2 (Syntaxin-binding protein 2, STXBP2, Unc18-2, Unc18B) is a 64-66kD member of the SNARE-interacting Sec1/Unc18/STXBP family of proteins. It is widely expressed, particularly in hematopoietic cells, and is found both in cytoplasm, and associated with membranes, where it binds to STX1A, 2 and 3. Thus, it presumably participates in primary granule exocytosis by promoting granule fusion. Human STXBP2 is 593aa in length. It contains one SEC1 domain (aa28-576) with Trp28, Ser42 and Glu59 all playing a key role in syntaxin binding. There is one splice variant that shows a deletion of aa83-85. Over aa80-223, human and mouse STXBP2 share 95% amino acid sequence identity. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Direct ELISA: 0.5-1ug/ml. The detection limit is ~1ng/well., Western Blot: 1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-Unc-18B, Anti-Protein unc-18 homolog 2, Anti-Protein unc-18 homolog B, Anti-Syntaxin-binding protein 2 |
Supplier: | United States Biological |
Supplier-Nr: | M2197-04 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human |
Immunogen: | E. coli-derived recombinant human STXBP2 (aa81-223, Accession # NP_001120868). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K15300 | Matching products |
UniProt ID : | Q15833 | Matching products |
Gene ID | GeneID 6813 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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