Anti-Mucin-5AC, clone SPM297

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-V9051SAF-100UG	100 µg		-	-	3 - 10 business days*		752.00€

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1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb recognizes the peptide core of... more

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Product information "Anti-Mucin-5AC, clone SPM297"

1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins. Protein function: Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. [The UniProt Consortium]

Keywords:	Anti-TBM, Anti-LeB, Anti-MUC-5AC, Anti-Mucin-5AC, Anti-Gastric mucin, Anti-Tracheobronchial mucin, Anti-Major airway glycoprotein, Anti-Lewis B blood group antigen, Anti-Mucin-5 subtype AC, tracheobronchial, Mucin-5AC Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	V9051SAF

Properties

Application:	FC, IF, IHC
Antibody Type:	Monoclonal
Clone:	SPM297
Conjugate:	No
Host:	Mouse
Species reactivity:	human, monkey, rabbit, cat, mouse, rat, swine, hedgehog, chicken
Immunogen:	An M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient was used as the immunogen for this Mucin-5AC antibody.
Format:	Purified