Anti-MUC5AC, clone YN01096m

Mucin 5AC (MUC5AC) is a group of high molecular weight glycoproteins, and its synthesis and secretion is one of the characteristics of glandular epithelial tissue. MUC5AC is normally expressed in gastric, ovarian, bronchial and other tissues, and forms a gel on the mucosal surface to protect the mucosa. MUC5AC protein expression can be observed in precancerous or cancerous tissues of colon, stomach, gallbladder and non-small cell lung cancer. Protein function: Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system (PubMed:14535999, PubMed:14718370). Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD) (PubMed:14535999). [The UniProt Consortium]