Anti-MUC16 / CA125, clone OCA125/2349R

Anti-MUC16 / CA125, clone OCA125/2349R
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3648-20UG 20 µg - -

3 - 10 business days*

263.00€
NSJ-V3648-100UG 100 µg - -

3 - 10 business days*

578.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. The mucins are a... more
Product information "Anti-MUC16 / CA125, clone OCA125/2349R"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions. Protein function: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. [The UniProt Consortium]
Keywords: Anti-CA-125, Anti-MUC-16, Anti-Mucin-16, Anti-Ovarian carcinoma antigen CA125, Anti-Ovarian cancer-related tumor marker CA125, MUC16 Antibody / CA125
Supplier: NSJ Bioreagents
Supplier-Nr: V3648

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: OCA125/2349R
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: A recombinant partial protein was used as the immunogen for the recombinant MUC16 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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