Anti-MUC-17 (Mucin-17) (human), Rabbit Monoclonal (RM517)

Anti-MUC-17 (Mucin-17) (human), Rabbit Monoclonal (RM517)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
REV-31-1409-00-R100 100 µl - -

3 - 9 business days*

541.00€
 
Membrane mucins have several functions in epithelial cells including cytoprotection,... more
Product information "Anti-MUC-17 (Mucin-17) (human), Rabbit Monoclonal (RM517)"
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC-17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. MUC-17 interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. MUC-17 probably plays a role in maintaining homeostasis on mucosal surfaces. Increased expression of this molecule has been reported in colon cancer.
Keywords: Anti-MUC3, Anti-MUC17, Anti-MUC-3, Anti-MUC-17, Anti-Mucin-17, Anti-Small intestinal mucin-3, Mucin-17, Small Intestinal Mucin-3 (MUC-3)
Supplier: RevMAb Biosciences
Supplier-Nr: 31-1409-00

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: RM517
Conjugate: No
Host: Rabbit
Species reactivity: human
Format: Liquid

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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