Anti-MTHFR

Anti-MTHFR
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES2863.50 50 µl - -

10 - 15 business days*

173.00€
ELK-ES2863.100 100 µl - -

10 - 15 business days*

290.00€
 
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to... more
Product information "Anti-MTHFR"
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009], Protein function: Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine (PubMed:29891918). Represents a key regulatory connection between the folate and methionine cycles (Probable). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000. Cellular localization: cytosol,synapse,
Keywords: Anti-Methylenetetrahydrofolate reductase (NADPH), MTHFR rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES2863

Properties

Application: WB, ELISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, monkey
Immunogen: The antiserum was produced against synthesized peptide derived from human MTHFR. AA range:314-363
MW: 75 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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