Anti-MST3/STK24

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-564A-T	10 µl (2 µg)		-		2 - 8 business days*		165.00€
A300-564A	100 µl		-		2 - 8 business days*		586.00€

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Protein function: Serine/threonine-protein kinase that acts on both serine and threonine residues... more

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Product information "Anti-MST3/STK24"

Protein function: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress- induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase- independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve. [The UniProt Consortium]

Keywords:	Anti-MST3, Anti-STK24, EC=2.7.11.1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-564A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A300-564A-T maps to a region between residues 325 and 375 of human Mammalian Ste20-like Kinase 3 (Serine/Threonine Kinase 24) using the numbering given in entry NP_003567.2 (GeneID 8428).
Format:	Antigen Affinity Purified