Anti-MSL2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES19715.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES19715.100	100 µl		-	-	10 - 14 business days*		290.00€

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Protein function: Component of histone acetyltransferase complex responsible for the majority of... more

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Product information "Anti-MSL2"

Protein function: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization:

Keywords:	Anti-MSL2, Anti-MSL-2, Anti-KIAA1585, EC=2.3.2.-, Anti-MSL2-like 1, Anti-RING finger protein 184, Anti-Male-specific lethal 2-like 1, Anti-Male-specific lethal-2 homolog, Anti-E3 ubiquitin-protein ligase MSL2, Anti-Male-specific lethal-2 homolog 1, MSL2 r
Supplier:	ELK Biotechnology
Supplier-Nr:	ES19715

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthesized peptide derived from human MSL2 AA range: 9-59
Format:	Purified