Anti-MSH3, clone RM405

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R20421-0.1ML	100 µl		-	-	3 - 10 business days*		772.00€

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Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This antibody reacts to human... more

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Product information "Anti-MSH3, clone RM405"

Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This antibody reacts to human to MSH3 / DNA mismatch repair protein Msh3. Protein function: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. [The UniProt Consortium]

Keywords:	Anti-DUP, Anti-MSH3, Anti-DUC1, Anti-MRP1, Anti-hMSH3, Anti-Mismatch repair protein 1, Anti-Divergent upstream protein, Anti-DNA mismatch repair protein Msh3, MSH3 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R20421

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Monoclonal
Clone:	RM405
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	peptide corresponding to residues near the N-terminus of human MSH3
Format:	Purified