Anti-MSH3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-314A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A305-314A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Component of the post-replicative DNA mismatch repair system (MMR).... more

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Product information "Anti-MSH3"

Protein function: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion- deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. [The UniProt Consortium]

Keywords:	Anti-DUP, Anti-DUC1, Anti-MRP1, Anti-MSH3, Anti-hMSH3, Anti-Mismatch repair protein 1, Anti-Divergent upstream protein, Anti-DNA mismatch repair protein Msh3
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-314A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A305-314A-T maps to a region between residue 1087 to 1137 of human DNA mismatch repair protein Msh3 using the numbering given in entry P20585.4 (GeneID 4437).
Format:	Antigen Affinity Purified