Anti-MRGPRX1 / MRGX1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59834.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: Orphan receptor. Probably involved in the function of nociceptive neurons. May... more

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Product information "Anti-MRGPRX1 / MRGX1"

Protein function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine- induced itch, in a histamine-independent manner. [The UniProt Consortium]

Keywords:	Anti-MRGX1, Anti-MRGPRX1, Anti-Mas-related G-protein coupled receptor member X1, Anti-Sensory neuron-specific G-protein coupled receptor 3/4
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59834

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse, rat
Immunogen:	Recombinant fusion protein corresponding to aa. 263-322 of Human MRGPRX1 (NP_671732.3)
MW:	36 kD
Format:	Affinity Purified