Anti-MPIG6B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA073017.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA073017.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Inhibitory receptor that acts as a critical regulator of hematopoietic lineage... more

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Product information "Anti-MPIG6B"

Protein function: Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production (PubMed:12665801, PubMed:17311996, PubMed:27743390). Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide (PubMed:12665801). This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling (PubMed:17311996). Appears to operate in a calcium-independent manner (PubMed:12665801). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 82% and to rat: 85%

Keywords:	Anti-Protein G6b, Anti-Megakaryocyte and platelet inhibitory receptor G6b
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA073017

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DRVNLSCGGV SHPIRWVWAP SFPACKGLSK GRRPILWASS SGTPTVPPLQ PFVGR (ATA-APrEST93109)