Anti-Mouse TNF alpha

Anti-Mouse TNF alpha
Item number Size Datasheet Manual SDS Delivery time Quantity Price
110-401-321S 25 µl - -

6 - 10 business days*

180.00€
 
This antiserum has been heated to 56°C for 30 minutes.  The antiserum is directed against mature... more
Product information "Anti-Mouse TNF alpha"
This antiserum has been heated to 56°C for 30 minutes.  The antiserum is directed against mature 17,000 MW mouse TNFa and is useful in determining its presence in various assays. The antibody does not recognize mouse TNFb (lymphotoxin).   This antiserum will recognize the cell-bound precursor of TNFa as a 26,000 protein in immunoblots, particularly in denatured samples.  This antibody is also useful for neutralization of mouse activity in bioassays.  It does not neutralize the biological activity of lymphotoxin.  For neutralization, it is recommended to incubate the sample with a 1:200 dilution of the antibody for at least 4 hours before being tested.  A control of similarly diluted normal rabbit IgG is recommended. Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. [The UniProt Consortium]
Keywords: Anti-Tnf, Anti-Tnfa
Supplier: Rockland Immunochemicals
Supplier-Nr: 110-401-321S

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse
Immunogen: recombinant mouse TNFa produced in E.coli.
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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