Anti-MonoMethyl-Histone H2B (Lys116) [R96-4G-1] Monoclonal Antibody

MonoMethyl-Histone H2B (Lys116) Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling , Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid [The Uniprot Consortium]