Anti-MOCS3

Anti-MOCS3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA027556.25 25 µl -

7 - 10 business days*

246.00€
ATA-HPA027556.100 100 µl -

7 - 10 business days*

491.00€
 
Protein function: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of... more
Product information "Anti-MOCS3"
Protein function: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor, NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 72% and to rat: 73%
Keywords: Anti-Sulfurtransferase MOCS3, Anti-MPT synthase sulfurylase, Anti-Adenylyltransferase MOCS3, Anti-Molybdopterin synthase sulfurylase, Anti-Molybdenum cofactor synthesis protein 3, Anti-Molybdopterin-synthase sulfurtransferase
Supplier: Atlas Antibodies
Supplier-Nr: HPA027556

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: FQDEILRSSR QLVLPELGVH RHVLVVGCGG LRCPLAQYLA AASVGRLGLV DYDVVEMSNL AYQVLHGEAL AAQAKAASAA ASLRGLNLAV E (ATA-APrEST70513)

Database Information

KEGG ID : K11996 | Matching products
UniProt ID : O95396 | Matching products
Gene ID : GeneID 27304 | Matching products
Protein Atlas Nr. : ENSG00000124217

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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