Anti-MNAT1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32131 100 µg - -

3 - 10 business days

503.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CDK-activating kinase assembly factor MAT1... more
Product information "Anti-MNAT1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CDK-activating kinase assembly factor MAT1 is an enzyme that in humans is encoded by the MNAT1 gene. The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. [The UniProt Consortium]
Keywords: Anti-p36, Anti-p35, Anti-MNAT1, Anti-CAP35, Anti-Menage a trois, Anti-RING finger protein 66, Anti-RING finger protein MAT1, Anti-Cyclin-G1-interacting protein, Anti-CDK7/cyclin-H assembly factor, Anti-CDK-activating kinase assembly factor MAT1, MNAT1 Ant
Supplier-Nr: R32131

Properties

Application: WB, IHC (paraffin)
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Amino acids 92-278 of human MNAT1 were used as the immunogen for the MNAT1 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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