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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R32131 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CDK-activating kinase assembly factor MAT1... more
Product information "Anti-MNAT1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CDK-activating kinase assembly factor MAT1 is an enzyme that in humans is encoded by the MNAT1 gene. The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. [The UniProt Consortium]
Keywords: | Anti-p36, Anti-p35, Anti-CAP35, Anti-MNAT1, Anti-Menage a trois, Anti-RING finger protein 66, Anti-RING finger protein MAT1, Anti-CDK7/cyclin-H assembly factor, Anti-Cyclin-G1-interacting protein, Anti-CDK-activating kinase assembly factor MAT1, MNAT1 Ant |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R32131 |
Properties
Application: | WB, IHC (paraffin), IF, FC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Amino acids 92-278 of human MNAT1 |
Format: | Purified |
Database Information
KEGG ID : | K10842 | Matching products |
UniProt ID : | P51948 | Matching products |
Gene ID | GeneID 4331 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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