Anti-MMADHC

Anti-MMADHC
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA037531.25 25 µl -

7 - 10 business days*

369.00€
ATA-HPA037531.100 100 µl -

7 - 10 business days*

491.00€
 
Protein function: Involved in cobalamin metabolism and trafficking (PubMed:18385497,... more
Product information "Anti-MMADHC"
Protein function: Involved in cobalamin metabolism and trafficking (PubMed:18385497, PubMed:23415655, PubMed:24722857, PubMed:26364851). Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl) (PubMed:18385497,PubMed:23415655, PubMed:24722857). Promotes oxidation of cob(II)alamin bound to MMACHC (PubMed:26364851). The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine (PubMed:27771510). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%
Keywords: Anti-CblD, Anti-C2orf25, Anti-HSPC161, Anti-Cobalamin trafficking protein CblD, Anti-Methylmalonic aciduria and homocystinuria type D protein, mitochondrial
Supplier: Atlas Antibodies
Supplier-Nr: HPA037531

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EVLLEKFING AKEICYALRA EGYWADFIDP SSGLAFFGPY TNNTLFETDE RYRHLGFSVD DLGCCKVIRH SLWGTHVVVG SIFTNAT (ATA-APrEST79190)

Database Information

UniProt ID : Q9H3L0 | Matching products
Gene ID : GeneID 27249 | Matching products
Protein Atlas Nr. : ENSG00000168288

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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