Anti-MMACHC

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-541A-T	10 µl (10 µg)		-		3 - 7 business days*		165.00€
A304-541A	100 µl (100 µg)		-		3 - 7 business days*		586.00€

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Protein function: Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using... more

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Product information "Anti-MMACHC"

Protein function: Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate (PubMed:19700356, PubMed:21697092, PubMed:22642810). Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione-dependent reductive demethylation of adenosylcobalamin (PubMed:19801555, PubMed:22642810, PubMed:25809485). Under anaerobic conditions cob(I)alamin is the first product, it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen (PubMed:19801555). Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives (PubMed:21071249). [The UniProt Consortium]

Keywords:	Anti-CblC, Anti-MMACHC, Anti-Cyanocobalamin reductase (cyanide-eliminating), Anti-Methylmalonic aciduria and homocystinuria type C protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-541A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine)
Immunogen:	synthetic peptide. The epitope recognized by A304-541A-T maps to a region between residue 175 to 225 of human Methylmalonic Aciduria and Homocystinuria Type C Protein using the numbering given in entry NP_056321.2 (GeneID 25974).
Format:	Antigen Affinity Purified