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Track device being used
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| NSJ-F54428-0.08ML | 80 µl | - | - |
3 - 10 business days* |
361.00€
|
||
| NSJ-F54428-0.4ML | 400 µl | - | - |
3 - 10 business days* |
772.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. MLF1 is involved in lineage commitment of primary... more
Product information "Anti-MLF1"
In 1X PBS, pH 7.4, with 0.09% sodium azide. MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. Protein function: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. [The UniProt Consortium]
| Keywords: | Anti-MLF1, Anti-Myeloid leukemia factor 1, Anti-Myelodysplasia-myeloid leukemia factor 1, MLF1 Antibody |
| Supplier: | NSJ Bioreagents |
| Supplier-Nr: | F54428 |
Properties
| Application: | IHC (paraffin), FC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | A portion of amino acids 215-244 from the human protein |
| Format: | Purified |
Database Information
| KEGG ID : | K15622 | Matching products |
| UniProt ID : | P58340 | Matching products |
| Gene ID : | GeneID 4291 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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