Anti-Mkl1 / MRTFA

Anti-Mkl1 / MRTFA
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG45214.50 50 µg - -

10 - 15 business days*

501.00€
 
Protein function: Transcription coactivator that associates with the serum response factor (SRF)... more
Product information "Anti-Mkl1 / MRTFA"
Protein function: Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration (PubMed:26224645). The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G- actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. MRTFA binds G-actin via its RPEL repeats, regulating activity of the MRTFA-SRF complex. Activity is also regulated by filamentous actin (F-actin) in the nucleus. [The UniProt Consortium]
Keywords: Anti-MRTF-A, Anti-MRTF-A, Anti-MKL/myocardin-like protein 1, Anti-MKL/myocardin-like protein 1, Anti-Megakaryoblastic leukemia 1 protein, Anti-Megakaryoblastic leukemia 1 protein, Anti-Megakaryocytic acute leukemia protein, Anti-Megakaryocytic acute leuke
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG45214

Properties

Application: ICC, IF, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant protein containing to human Mkl1 / MRTFA
MW: 98 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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