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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ABS-KC-2359.50 | 50 µl | - | - |
Request delivery time estimate |
206.00€
|
||
| ABS-KC-2359.100 | 100 µl | - | - |
Request delivery time estimate |
295.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm... more
Product information "Anti-MKI67"
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). [The UniProt Consortium]
| Keywords: | Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by monoclonal antibody Ki-67, Anti-Antigen KI-67, Anti-Antigen Ki67, MKI67 Antibody |
| Supplier: | Absea |
| Supplier-Nr: | KC-2359 |
Properties
| Application: | IHC |
| Antibody Type: | Monoclonal |
| Clone: | 5F11 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
| Immunogen: | Recombinant human MKI67 |
| Format: | Solution |
Database Information
| KEGG ID : | K17582 | Matching products |
| UniProt ID : | P46013 | Matching products |
| Gene ID : | GeneID 4288 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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