Anti-MICU2

Anti-MICU2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA074608.25 25 µl

3 - 8 business days*

369.00€
ATA-HPA074608.100 100 µl

3 - 8 business days*

491.00€
 
Rabbit Polyclonal MICU2 Antibody against Human mitochondrial calcium uptake 2. Validated for... more
Product information "Anti-MICU2"
Rabbit Polyclonal MICU2 Antibody against Human mitochondrial calcium uptake 2. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000021973: 96%, ENSRNOG00000011168: 96%. Protein function: Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF- hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927). [The UniProt Consortium]
Keywords: Anti-EFHA1, Anti-MICU2, Anti-Calcium uptake protein 2, mitochondrial, Anti-EF-hand domain-containing family member A1
Supplier: Atlas Antibodies
Supplier-Nr: HPA074608

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: LQFSKGLSFM RKEDFAEWLL FFTNTENKDI YWKNVREKLS AGESISLDEF KSFCHFTTHL EDFAIAMQMF SLAHRPVRLA
Format: Affinity Purified

Handling & Safety

Storage: -20°C (+4 °C for short term storage)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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