Anti-MICU2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA045511.25	25 µl		-		3 - 8 business days*		246.00€
ATA-HPA045511.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Key regulator of mitochondrial calcium uniporter (MCU) required to limit... more

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Product information "Anti-MICU2"

Protein function: Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF- hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 80% and to rat: 76%

Keywords:	Anti-MICU2, Anti-EFHA1, Anti-Calcium uptake protein 2, mitochondrial, Anti-EF-hand domain-containing family member A1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA045511

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LAAAVAGAAL AGAGAAWHHS RVSVAARDGS FTVSAQKNVE HGIIYIGKPS LRKQRFMQFS SLEHEGEYYM TPRDFLFSVM FEQMERKTSV KKLTKKDIED TLSGIQT (ATA-APrEST81358)