Anti-MHC I(246-B8E7), CF488A conjugate, 0.1mg/mL

Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.Primary antibodies are available purified, or with a selection of fluorescent CF(R) Dyes and other labels. CF(R) Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF(R)405S and CF(R)405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. Concentration: 0.1 mg/mL Storage buffer: PBS, 0.1% BSA, 0.05% azide