Anti-Metabotropic Glutamate Receptor 5 [R08-4I1] Monoclonal Antibody

Metabotropic Glutamate Receptor 5 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity [The Uniprot Consortium]