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Protein function: Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell- surface expression of LRP4. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells. [The UniProt Consortium]
Keywords:
Anti-KIAA0081, Anti-LRP chaperone MESD, Anti-LDLR chaperone MESD, Anti-Mesoderm development protein, Anti-Mesoderm development candidate 2, Anti-Renal carcinoma antigen NY-REN-61, Anti-Mesoderm development LRP chaperone MESD, MESDC2 Polyclonal Antibody
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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