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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R30572 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. MAP3K2, mitogen-activated protein kinase... more
Product information "Anti-MEKK2"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. MAP3K2, mitogen-activated protein kinase kinase kinase 2, also known as MEKK2, belongs to the mitogen-activated protein kinase(MAPK) kinase kinase gene family, which is involved in regulating multiple MAPK signaling pathways. Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts. The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium. MAP3K2 is a major upstream activator of the JNK, MAPK cascade. MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle. Silencing of MAP3K2 strongly reduced kiss-and-run dynamics, leading to an accumulation of caveolar structures at the cell surface without affecting caveolae coat assembly or clustering. Protein function: Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss-and-run dynamics. [The UniProt Consortium]
Keywords: | Anti-MEKK 2, Anti-MAP3K2, Anti-MAPKKK2, EC=2.7.11.25, Anti-MEK kinase 2, Anti-MAPK/ERK kinase kinase 2, Anti-Mitogen-activated protein kinase kinase kinase 2, MEKK2 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R30572 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | An amino acid sequence from the C-terminus of human MEKK2 (SADELLRHMFVHYH) was used as the immunogen for this MEKK2 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K04420 | Matching products |
UniProt ID : | Q9Y2U5 | Matching products |
Gene ID | GeneID 10746 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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