Anti-MEF2B, clone PCRP-MEF2B-2F9

Anti-MEF2B, clone PCRP-MEF2B-2F9
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V9641SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. The myocyte enhancer factor-2 (MEF-2) family of... more
Product information "Anti-MEF2B, clone PCRP-MEF2B-2F9"
1 mg/ml in 1X PBS, BSA free, sodium azide free. The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes. Protein function: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription. [The UniProt Consortium]
Keywords: Anti-XMEF2, Anti-MEF2B, Anti-RSRFR2, Anti-Myocyte-specific enhancer factor 2B, Anti-Serum response factor-like protein 2, MEF2B Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V9641SAF

Properties

Application: WB, FC, IF
Antibody Type: Monoclonal
Clone: PCRP-MEF2B-2F9
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant full-length human MEF2B protein
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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