Anti-MEF2A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-531A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-531A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Transcriptional activator which binds specifically to the MEF2 element,... more

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Product information "Anti-MEF2A"

Protein function: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter. [The UniProt Consortium]

Keywords:	Anti-MEF2, Anti-MEF2A, Anti-Myocyte-specific enhancer factor 2A, Anti-Serum response factor-like protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-531A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: chicken, orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A303-531A-T maps to a region between residue 175 and 225 of human Myocyte Enhancer Factor 2A using the numbering given in entry CAA48517.1 (GeneID 4205).
Format:	Antigen Affinity Purified