Anti-MCM7, clone MMCC7-1R

Anti-MCM7, clone MMCC7-1R
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7360-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V7360-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Acts as component of... more
Product information "Anti-MCM7, clone MMCC7-1R"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage. [UniProt] Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage. [The UniProt Consortium]
Keywords: Anti-MCM7, Anti-CDC47, Anti-P1.1-MCM3, EC=3.6.4.12, Anti-CDC47 homolog, Anti-DNA replication licensing factor MCM7, MCM7 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V7360

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: MMCC7-1R
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Amino acids 195-319 from the human protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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