Anti-MBNL2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA062685.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA062685.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or... more

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Product information "Anti-MBNL2"

Protein function: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. Seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm at adhesion plaques. May play a role in myotonic dystrophy pathophysiology (DM). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 96%

Keywords:	Anti-MBLL, Anti-MBNL2, Anti-Muscleblind-like protein 1, Anti-Muscleblind-like protein 2, Anti-Muscleblind-like protein-like, Anti-Muscleblind-like protein-like 39
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA062685

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AMLAQQMQFM FPGTPLHPVP TFPVGPAIGT NTAISFAPYL APVTPGVGLV (ATA-APrEST89996)