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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ5986 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Methyl-CpG-binding domain protein 4 is a... more
Product information "Anti-MBD4"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene. It is mapped to 3q21.3. The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Protein function: Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. [The UniProt Consortium]
Keywords: | Anti-MED1, Anti-MBD4, EC=3.2.2.-, Anti-Methyl-CpG-binding protein MBD4, Anti-Methyl-CpG-binding endonuclease 1, Anti-Mismatch-specific DNA N-glycosylase, Anti-Methyl-CpG-binding domain protein 4, MBD4 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ5986 |
Properties
Application: | WB, IHC (paraffin), IF, FC, Direct ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant human protein (amino acids A16-S580) |
Format: | Purified |
Database Information
KEGG ID : | K10801 | Matching products |
UniProt ID : | O95243 | Matching products |
Gene ID | GeneID 8930 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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