Anti-MAZ / Myc associated zinc finger protein

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. MAZ antibody detects Myc associated zinc finger protein, encoded by the MAZ gene. Myc associated zinc finger protein is a transcription factor that regulates gene expression through GC-rich DNA elements and is involved in cell growth, apoptosis, and oncogenesis. MAZ antibody provides researchers with a critical reagent for studying transcriptional regulation and cancer biology.Myc associated zinc finger protein belongs to the Kruppel family of zinc finger proteins and contains six C2H2-type zinc fingers. Research using MAZ antibody has shown that it binds to GC-rich promoter elements and initiator regions, where it regulates transcription of a wide range of genes. These include c-Myc, VEGF, and insulin receptor genes, linking MAZ to proliferation, angiogenesis, and metabolism.Studies with MAZ antibody have revealed that the protein has dual transcriptional roles, functioning as both an activator and repressor depending on context. It recruits transcriptional co-regulators and chromatin remodelers, fine-tuning expression of growth-related genes. This versatility makes MAZ a central node in transcriptional networks controlling development and disease.Dysregulation of Myc associated zinc finger protein has been associated with cancer, cardiovascular disease, and neurodegeneration. Research using MAZ antibody has shown that overexpression promotes tumor growth and angiogenesis by upregulating VEGF and c-Myc. It has also been implicated in atherosclerosis, where it regulates vascular smooth muscle proliferation, and in neurodegenerative disorders, where altered transcription contributes to pathology.MAZ antibody is commonly used in chromatin immunoprecipitation, western blotting, and immunohistochemistry. Chromatin immunoprecipitation identifies promoter binding sites, western blotting quantifies expression in normal and cancer tissues, and immunohistochemistry demonstrates nuclear localization in proliferating cells. These applications make MAZ antibody valuable for transcriptional and oncogenesis research.By supplying validated MAZ antibody reagents, NSJ Bioreagents supports studies into transcriptional control, oncogenesis, and vascular biology. Detection of Myc associated zinc finger protein provides researchers with insight into how zinc finger proteins regulate gene expression and disease.