Anti-MASTL

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-190A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-190A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-190A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Serine/threonine kinase that plays a key role in M phase by acting as a... more
Product information "Anti-MASTL"
Protein function: Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro, however such activity is unsure in vivo. May be involved in megakaryocyte differentiation. [The UniProt Consortium]
Keywords: Anti-GW, Anti-GWL, Anti-hGWL, Anti-MASTL, Anti-MAST-L, EC=2.7.11.1, Anti-Serine/threonine-protein kinase greatwall, Anti-Microtubule-associated serine/threonine-protein kinase-like
Supplier: Bethyl Laboratories
Supplier-Nr: A302-190A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: synthetic peptide. The epitope recognized by A302-190A-T maps to a region between residue 550 and 600 of human microtubule associated serine/threonine kinase-like using the numbering given in entry NP_116233.2 (GeneID 84930).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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