Anti-MARK3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-186A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-186A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Involved in the specific phosphorylation of microtubule- associated proteins... more

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Product information "Anti-MARK3"

Protein function: Involved in the specific phosphorylation of microtubule- associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714). [The UniProt Consortium]

Keywords:	Anti-MARK3, Anti-CTAK1, Anti-cTAK1, Anti-EMK-2, Anti-C-TAK1, Anti-Par-1a, EC=2.7.11.1, Anti-ELKL motif kinase 2, Anti-Protein kinase STK10, Anti-Ser/Thr protein kinase PAR-1, Anti-Cdc25C-associated protein kinase 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-186A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: chicken, horse, rhesus monkey, gorilla, chimpanzee, duckbill platypus, thirteen-lined ground squirrel, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-186A-T maps to a region between residue 525 and 575 of human MAP/microtubule affinity-regulating kinase 3 using the numbering given in entry EAW81819.1 (GeneID 4140).
Format:	Antigen Affinity Purified