Anti-MARCH5

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES6673.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES6673.100 100 µl - -

10 - 14 business days*

290.00€
 
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control... more
Product information "Anti-MARCH5"
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2, MIM 608507) and DRP1 (DNM1L, MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008], Protein function: Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Mitochondrion outer membrane , Multi-pass membrane protein . Endoplasmic reticulum membrane , Multi-pass membrane protein . Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266). Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301). .
Keywords: Anti-MITOL, Anti-MARCH5, Anti-MARCH-V, EC=2.3.2.27, Anti-RING finger protein 153, Anti-Mitochondrial ubiquitin ligase, Anti-E3 ubiquitin-protein ligase MARCHF5, Anti-Membrane-associated RING-CH protein V, Anti-Membrane-associated RING finger protein 5, MA
Supplier: ELK Biotechnology
Supplier-Nr: ES6673

Properties

Application: IF, WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: The antiserum was produced against synthesized peptide derived from human MARCH5. AA range:21-70
MW: 37 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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