Anti-MAML1 / Mastermind, N-terminal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG63575.100	100 µg		-	-	6 - 14 business days*		871.00€

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Protein function: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to... more

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Product information "Anti-MAML1 / Mastermind, N-terminal"

Protein function: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions. [The UniProt Consortium]

Keywords:	Anti-Mam-1, Anti-Mastermind-like protein 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG63575

Properties

Application:	ELISA, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human (Expected: mouse)
Immunogen:	VLPTCPMAEFALPR
Format:	Ammonium Sulfate Precipitated