Anti-MAML1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA057531.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA057531.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to... more

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Product information "Anti-MAML1"

Protein function: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 81% and to rat: 80%

Keywords:	Anti-Mam-1, Anti-Mastermind-like protein 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA057531

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PQAGNLMPMG PGHASVSSLP TNSGQQDRGV AQFPGSQNMP QSSLYGMASG ITQIVAQPPP QATNGHAHIP RQTNVGQNT (ATA-APrEST91820)