Anti-MAGE-1, clone MAAZ2

Anti-MAGE-1, clone MAAZ2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7116IHC-7ML 7 ml - -

3 - 10 business days*

752.00€
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. The... more
Product information "Anti-MAGE-1, clone MAAZ2"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy. Protein function: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. [The UniProt Consortium]
Keywords: Anti-CT1.1, Anti-MAGE1, Anti-MAGEA1, Anti-Antigen MZ2-E, Anti-MAGE-1 antigen, Anti-Cancer/testis antigen 1.1, Anti-Melanoma-associated antigen 1, MAGE-1 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V7116IHC

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: MAAZ2
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant human MAGEA1 protein was used as the immunogen for the MAGE-1 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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